Article
Hepatocyte growth factor effects on mesenchymal stem cells: proliferation, migration, and differentiation.
Stem cells (Dayton, Ohio) - 1 Jan 2006
Forte Giancarlo, Minieri Marilena, Cossa Paolo, Antenucci Daniele, Sala Marilena, Gnocchi Viola, Fiaccavento Roberta, Carotenuto Felicia, De Vito Paolo, Baldini Patrizia Morena, Prat Maria, Di Nardo Paolo
Abstract excerpt
Hepatocyte growth factor (HGF), a pleiotropic cytokine of mesenchymal origin promoting migration, proliferation, and survival in a wide spectrum of cells, can also modulate different biological responses in stem cells, but the mechanisms involved are not completely understood so far. In this context, we show that short-term exposure of mesenchymal stem cells (MSCs) to HGF can induce the activation of its cognate...
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