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A Proteomics Analysis of Cell Signaling Alterations in Colorectal Cancer

11 Sept 2007

Abstract excerpt

To gain further insight into alterations in cellular pathways, tumor profiling, and marker discovery in colorectal cancer (CRC) we used a new antibody microarray specific for cell signaling. Soluble protein extracts were prepared from paired tumor/normal biopsies of 11 patients diagnosed with colorectal carcinoma at different stages; four liver carcinomas were used as a reference. Antibody microarray analysis...

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PMID: 17848589
DOI: 10.1074/mcp.m700006-mcp200

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