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Article

The MTHFR 677C --> T polymorphism and risk of prostate cancer: results from the CAPS study.

Cancer causes & control : CCC - 1 Dec 2007

Johansson Mattias, Van Guelpen Bethany, Hultdin Johan, Wiklund Fredrik, Adami Hans-Olov, Bälter Katarina, Grönberg Henrik, Stattin Pär

Abstract excerpt

The methylenetetrahydrafolate reductase (MTHFR) enzyme may influence cancer development by affecting DNA methylation, synthesis and repair. The MTHFR 677C-->T single nucleotide polymorphism (SNP) has been associated with decreased enzyme activity and has therefore been implicated in cancer development. We analyzed the MTHFR 677C-->T SNP in 2,777 incident prostate cancer cases and 1,639 population controls from...

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Identifiers

PMID: 17846906
DOI: 10.1007/s10552-007-9055-z

Genes

MTHFR
CAPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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