Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A role of monocyte chemoattractant protein-4 (MCP-4)/CCL13 from chondrocytes in rheumatoid arthritis.

The FEBS journal - 1 Sept 2007

Iwamoto Takuji, Okamoto Hiroshi, Kobayashi Shu, Ikari Katsunori, Toyama Yoshiaki, Tomatsu Taisuke, Kamatani Naoyuki, Momohara Shigeki

Abstract excerpt

We studied the role of monocyte chemoattractant (MCP)-4/CCL13 in the pathogenesis of rheumatoid arthritis (RA). MCP-4 was highly expressed in cartilage from RA patients. Interferon-gamma significantly stimulated MCP-4/CCL13 production in human chondrocytes, and this effect was enhanced in combination with interleukin-1beta or tumor necrosis factor-alpha. MCP-4/CCL13 induces the phosphorylation of extracellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chondrocytes

Share to Extracellular Signal-Regulated MAP Kinases

Share to Phosphorylation

Share to Polymorphism, Single Nucleotide

Share to RNA, Messenger

Source

Identifiers

PMID: 17824960
DOI: 10.1111/j.1742-4658.2007.06013.x

Genes

CCL13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

A role of monocyte chemoattractant protein-4 (MCP-4)/CCL13 from chondrocytes in rheumatoid arthritis.PMID 17824960Read ↗

Eotaxin-1/CCL11 is involved in cell migration in rheumatoid arthritisSemantic proximity Read ↗

C-Reactive Protein Promotes the Activation of Fibroblast-Like Synoviocytes From Patients With Rheumatoid Arthritis.Semantic proximity Read ↗

Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritis.Semantic proximity Read ↗

Macrophage migration inhibitory factor in rheumatoid arthritis.Semantic proximity Read ↗

Chemokine Signaling Pathway Involved in CCL2 Expression in Patients with Rheumatoid ArthritisSemantic proximity Read ↗

CCAAT/enhancer-binding protein β and NF-κB mediate high level expression of chemokine genes CCL3 and CCL4 by human chondrocytes in response to IL-1β.Semantic proximity Read ↗

15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts.Semantic proximity Read ↗

Modulation of monocyte chemotactic function in inflammatory lesions. Role of inflammatory mediators.Semantic proximity Read ↗

IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways.Semantic proximity Read ↗

Monocyte Chemotactic Protein-3 (MCP3) Interacts with Multiple Leukocyte ReceptorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.