Article
Successful virological outcome in an HIV-infected individual with a three-class resistant variant and an insertion in the protease genome with a Tipranavir based regimen.
Irish journal of medical science - 1 Jun 2010
Panagopoulos P, Paraskevis D, Antoniadou A, Papadopoulos A, Poulakou G, Hatzakis A, Giamarellou H
Abstract excerpt
BACKGROUND: Multi-class HIV-1 resistant variants are not rare nowadays. Genotypic and phenotypic resistance testing (including virtual phenotype) constitutes an important tool for optimizing antiretroviral treatment. AIM: To report a case of discrepancy between resistance interpretation and virological outcome. METHODS: A case of a multi-drug experienced patient is presented. Genotypic and/or virtual phenotypic...
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