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Article

Vanadate-resistant mutants of Candida albicans show alterations in phosphate uptake.

FEMS microbiology letters - 15 Nov 1991

Mahanty S K, Khaware R, Ansari S, Gupta P, Prasad R

Abstract excerpt

Phosphate uptake studies in different strains of the dimorphic pathogenic yeast Candida albicans were undertaken to show that this yeast actively transported phosphate with an apparent Km in the range of 90-170 microM. The uptake was pH dependent and derepressible under phosphate starvation. Vanadate-resistant (van) mutants of C. albicans showed a 20-70% reduction in the rate of phosphate uptake in high phosphate...

Topics

Biological Transport
Candida albicans
Drug Resistance, Microbial
Hydrogen-Ion Concentration
Kinetics
Mutation
Phosphates
Vanadates

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1778439
DOI: 10.1016/0378-1097(91)90121-p

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1778439-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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