Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zinc up-regulates NF-kappaB activation via phosphorylation of IkappaB in HUT-78 (Th0) cells.

FEBS letters - 18 Sept 2007

Bao Bin, Prasad Ananda S, Beck Frances W J, Sarkar Fazlul H

Abstract excerpt

Nuclear factor of kappaB (NF-kappaB) is a major transcription factor regulating the expression of interleukin-2 (IL-2) and interleukin-2 receptor-alpha (IL-2Ralpha) in Th(1) cells. We previously demonstrated that zinc increased IL-2 and IL-2Ralpha production via NF-kappaB activation in HUT-78 (Th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Western
Share to Electrophoretic Mobility Shift Assay
Share to I-kappa B Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-2

Share to Interleukin-2 Receptor alpha Subunit

Share to Microscopy, Confocal

Share to NF-kappa B

Source

Identifiers

PMID: 17765898
DOI: 10.1016/j.febslet.2007.08.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17765898-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Zinc up-regulates NF-kappaB activation via phosphorylation of IkappaB in HUT-78 (Th0) cells.PMID 17765898Read ↗

Effects of zinc deficiency on immune functionsSemantic proximity Read ↗

Cytoplasmic zinc regulates IL-1β production by monocytes/macrophages via mTORC1-induced glycolysis in rheumatoid arthritis (RA)Semantic proximity Read ↗

Role of NF-kappaB in the control of apoptotic and proliferative responses in IL-2-responsive T cellsSemantic proximity Read ↗

The zinc finger mutation C417R of I-kappa B kinase gamma impairs lipopolysaccharide- and TNF-mediated NF-kappa B activation through inhibiting phosphorylation of the I-kappa B kinase beta activation loop.Semantic proximity Read ↗

New Insights into the Role of Nuclear Factor-κB, a Ubiquitous Transcription Factor in the Initiation of DiseasesSemantic proximity Read ↗

Regulation of the Immune System by NF-κB and IκBSemantic proximity Read ↗

Roles of NF-κB in health and disease: mechanisms and therapeutic potentialSemantic proximity Read ↗

The central inflammatory regulator IκBζ: induction, regulation and physiological functionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.