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Article

Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations.

Arthritis and rheumatism - 1 Sept 2007

Gattorno Marco, Tassi Sara, Carta Sonia, Delfino Laura, Ferlito Francesca, Pelagatti Maria Antonietta, D'Osualdo Andrea, Buoncompagni Antonella, Alpigiani Maria Giannina, Alessio Maria, Martini Alberto, Rubartelli Anna

Abstract excerpt

OBJECTIVE: To examine the synthesis, processing, and secretion of interleukin-1beta (IL-1beta), as well as the clinical and biologic effects of IL-1 blockade, in patients with chronic infantile neurologic, cutaneous, articular (CINCA) syndrome and Muckle-Wells syndrome (MWS), in an effort to understand the molecular mechanisms linking mutations of the CIAS1 gene and IL-1beta hypersecretion, and the underlying...

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PMID: 17763411
DOI: 10.1002/art.22842

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations.PMID 17763411Read ↗

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