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Article

A severe case of chronic infantile neurologic, cutaneous, articular syndrome treated with biologic agents.

Arthritis and rheumatism - 1 Jul 2006

Matsubara Tomoyo, Hasegawa Masanari, Shiraishi Masahiro, Hoffman Hal M, Ichiyama Takashi, Tanaka Takeo, Ueda Haruo, Ishihara Tokuhiro, Furukawa Susumu

Abstract excerpt

In this report we describe a case of severe chronic infantile neurologic, cutaneous, articular (CINCA) syndrome with a novel G307V cryopyrin mutation and all of the characteristic clinical and laboratory features of this autoinflammatory disease. There was no clear response to standard therapies, including human interleukin-1 (IL-1) receptor antagonist (anakinra) and soluble tumor necrosis factor receptor...

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Identifiers

PMID: 16802372
DOI: 10.1002/art.21965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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A severe case of chronic infantile neurologic, cutaneous, articular syndrome treated with biologic agents.PMID 16802372Read ↗

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