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Article

Early developmental pathology due to cytochrome c oxidase deficiency is revealed by a new zebrafish model.

The Journal of biological chemistry - 30 Nov 2007

Baden Katrina N, Murray James, Capaldi Roderick A, Guillemin Karen

Abstract excerpt

Deficiency of cytochrome c oxidase (COX) is associated with significant pathology in humans. However, the consequences for organogenesis and early development are not well understood. We have investigated these issues using a zebrafish model. COX deficiency was induced using morpholinos to reduce...

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Identifiers

PMID: 17761683
DOI: 10.1074/jbc.M703528200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17761683-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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