Article
Seeking causes: Classifying and evaluating congenital heart defects in etiologic studies.
Birth defects research. Part A, Clinical and molecular teratology - 1 Oct 2007
Botto Lorenzo D, Lin Angela E, Riehle-Colarusso Tiffany, Malik Sadia, Correa Adolfo
Abstract excerpt
BACKGROUND: Classification and analysis of congenital heart defects (CHD) in etiologic studies is particularly challenging because of diversity of cardiac phenotypes and underlying developmental mechanisms. We describe an approach to classification for risk assessment of CHD based on developmental and epidemiologic considerations, and apply it to data from the National Birth Defect Prevention Study (NBDPS)....
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