Article
Importance of N-linked glycosylation in the functional expression of murine CD1d1.
Immunology - 1 Feb 2008
Sriram Venkataraman, Willard Claire A, Liu Jianyun, Brutkiewicz Randy R
Abstract excerpt
The mouse CD1d1 glycoprotein is specialized in presenting lipid antigens to a novel class of T cells called natural killer T (NKT) cells. CD1d1 is predicted to contain five potential N-linked glycosylation sites (asparagine residues at positions 25, 38, 60, 128, and 183). Glycosylation has been shown to invariably affect the molecular and functional properties of various glycoproteins, and in the current report...
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