Article
An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii.
Antimicrobial agents and chemotherapy - 1 Nov 2007
Hu Wensi S, Yao Shu-Man, Fung Chang-Phone, Hsieh Yi-Ping, Liu Chang-Pan, Lin Jing-Fang
Abstract excerpt
We investigated the mechanisms involved in imipenem resistance in 23 clinical strains of Acinetobacter baumannii. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis showed the presence of a 30-kDa protein in imipenem-intermediate A. baumannii (IIAB) and imipenem-resistant A. baumannii (IRAB) strains; this protein was almost undetectable in imipenem-susceptible A. baumannii (ISAB)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
