Article
Tertiary structural analysis of the elongated part of an abnormal hemoglobin, hemoglobin Pakse.
International journal of nanomedicine - 1 Jan 2006
Wiwanitkit Viroj
Abstract excerpt
Hemoglobin variants in which a frameshift results in chain elongation are unusual. Hemoglobin Pakse (Hb Pakse) is an unstable hemoglobin with abnormal elongation, first described in Indochina. An alpha2-globin gene termination codon mutation, TAA -->TAT or Term -->Tyr, has been described in the pathogenesis of Hb Pakse. This abnormality causes a frameshift that elongates the alpha chain amino acids....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
