Article
CYP2C9 and VKORC1 genetic polymorphism analysis might be necessary in patients with Factor V Leiden and prothrombin gene G2021A mutation(s).
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2007
Leung Allen, Huang Chih-Kang, Muto Riho, Liu Yinxian, Pan Qiulu
Abstract excerpt
The annual incidence of venous thromboembolism is approximately 117 per 100,000 persons or about 1 per 1000 person-years, with the majority of the disease occurring in the older age groups. Factor V Leiden gene (most common) and the prothrombin G20210A gene mutation are inherited mild to moderate risk factors for hypercoagulability. The anticoagulant warfarin requires close monitoring of the patient's prothrombin...
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