Article
Association between KCNJ11 E23K genotype and cardiovascular and glucose metabolism phenotypes in older men and women.
Experimental physiology - 1 Jan 2008
Yi Yang, Dongmei Liu, Phares Dana A, Weiss Edward P, Brandauer Josef, Hagberg James M
Abstract excerpt
Our objective was to investigate the relationship between the E23K genetic variant in the KCNJ11 gene, which encodes for the Kir6.2 subunit of the inward rectifier K+ channel family, and glucose and insulin metabolism and cardiovascular (CV) function in the sedentary state and their responses to exercise training. Two hundred and fourteen healthy sedentary men and women aged 50-75 years old and free of CV disease...
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