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Article

Association of Escherichia coli O157:H7 tir polymorphisms with human infection.

BMC infectious diseases - 24 Aug 2007

Bono James L, Keen James E, Clawson Michael L, Durso Lisa M, Heaton Michael P, Laegreid William W

Abstract excerpt

BACKGROUND: Emerging molecular, animal model and epidemiologic evidence suggests that Shiga-toxigenic Escherichia coli O157:H7 (STEC O157) isolates vary in their capacity to cause human infection and disease. The translocated intimin receptor (tir) and intimin (eae) are virulence factors and bacterial receptor-ligand proteins responsible for tight STEC O157 adherence to intestinal epithelial cells. They represent...

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Identifiers

PMID: 17718910
DOI: 10.1186/1471-2334-7-98
PMCID: PMC2063500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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