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Article

The capsid and tegument of the alphaherpesviruses are linked by an interaction between the UL25 and VP1/2 proteins.

Journal of virology - 1 Nov 2007

Coller Kelly Elizabeth, Lee Joy I-Hsuan, Ueda Aki, Smith Gregory Allan

Abstract excerpt

How alphaherpesvirus capsids acquire tegument proteins remains a key question in viral assembly. Using pseudorabies virus (PRV), we have previously shown that the 62 carboxy-terminal amino acids of the VP1/2 large tegument protein are essential for viral propagation and when transiently expressed as a fusion to green fluorescent protein relocalize to nuclear capsid assemblons following viral infection. Here, we...

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Identifiers

PMID: 17715218
DOI: 10.1128/JVI.01113-07
PMCID: PMC2168758

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