Article
HLA-DQ haplotypes in Spanish and German families with Graves' disease: contribution to DQA1*0501-DQB1*0301 mediated genetic susceptibility from fathers.
Thyroid : official journal of the American Thyroid Association - 1 Nov 2007
Ramos-Lopez Elizabeth, Fernandez-Balsells Mercedes, Kahles Heinrich, Seidl Christian, Ferrer Jorge, Badenhoop Klaus
Abstract excerpt
Genetic and environmental factors are involved in the pathogenesis of Graves' disease. The human leukocyte antigen (HLA) locus is considered to be one risk factor for Graves' disease but parent of origin effects have not been studied. Therefore, we investigated the transmission of HLA risk haplot...
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