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Article

Identification of genomic changes associated with cisplatin resistance in testicular germ cell tumor cell lines.

Genes, chromosomes & cancer - 1 Jul 2008

Noel Elodie E, Perry Jackie, Chaplin Tracy, Mao Xueying, Cazier Jean-Baptiste, Joel Simon P, Oliver R Tim D, Young Bryan D, Lu Yong-Jie

Abstract excerpt

Since the introduction of cisplatin into the clinic, the treatment of patients with a variety of solid tumors including testicular germ cell tumors, ovarian and lung cancers, has dramatically improved. One of the main causes for therapeutic failure in these malignancies is the development of drug resistance. Testicular germ cell tumors (TGCTs), the most common malignancy in young men, exhibit extreme sensitivity...

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

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Share to In Situ Hybridization, Fluorescence

Share to Microarray Analysis

Share to Testicular Neoplasms

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 18384131
DOI: 10.1002/gcc.20564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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