Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sporadic adult onset dystonia: sensory abnormalities as an endophenotype in unaffected relatives.

Journal of neurology, neurosurgery, and psychiatry - 1 Sept 2007

Walsh Richard, O'Dwyer John P, Sheikh Ifthikar H, O'Riordan Sean, Lynch Tim, Hutchinson Michael

Abstract excerpt

BACKGROUND: Most patients with adult onset primary torsion dystonia (AOPTD) have the sporadic form of the disease. They may however be the only manifesting family members of a poorly penetrant genetic disorder. Sensory changes, including structural abnormalities of the primary sensory cortex, are found in AOPTD. Spatial discrimination threshold (SDT), a measure of sensory cortical organisation, is abnormal in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Botulinum Toxin and Related Neurological Disorders
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dystonic Disorders

Share to Heterozygote

Share to Neurological disorders and treatments

Share to Phenotype

Share to Sensation

Share to Space Perception

Source

Open in PubMed Open full text

Identifiers

PMID: 17702779
DOI: 10.1136/jnnp.2006.105585
PMCID: PMC2117873

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sporadic adult onset dystonia: sensory abnormalities as an endophenotype in unaffected relatives.PMID 17702779Read ↗

Sensory abnormalities in unaffected relatives in familial adult-onset dystonia.Semantic proximity Read ↗

Striatal morphology correlates with sensory abnormalities in unaffected relatives of cervical dystonia patients.Semantic proximity Read ↗

Sporadic adult onset primary torsion dystonia is a genetic disorder by the temporal discrimination testSemantic proximity Read ↗

Temporal discrimination threshold: VBM evidence for an endophenotype in adult onset primary torsion dystonia.Semantic proximity Read ↗

Comparing endophenotypes in adult-onset primary torsion dystonia.Semantic proximity Read ↗

The endophenotype and the phenotype: temporal discrimination and adult-onset dystonia.Semantic proximity Read ↗

Temporal discrimination thresholds in adult-onset primary torsion dystonia: an analysis by task type and by dystonia phenotype.Semantic proximity Read ↗

Temporal discrimination, a cervical dystonia endophenotype: Penetrance and functional correlatesSemantic proximity Read ↗

Defective temporal processing of sensory stimuli in DYT1 mutation carriers: a new endophenotype of dystonia?Semantic proximity Read ↗

Age at onset as a factor in determining the phenotype of primary torsion dystonia.Semantic proximity Read ↗

Neural correlates of abnormal sensory discrimination in laryngeal dystonia.Semantic proximity Read ↗

Do primary adult-onset focal dystonias share aetiological factors?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.