Article
Sensory abnormalities in unaffected relatives in familial adult-onset dystonia.
Neurology - 27 Sept 2005
O'Dwyer J P, O'Riordan S, Saunders-Pullman R, Bressman S B, Molloy F, Lynch T, Hutchinson M
Abstract excerpt
Somatosensory abnormalities are found in adult-onset primary torsion dystonia (PTD). Therefore we assessed spatial discrimination thresholds (SDT), a measure of spatial acuity, in four multiplex families with adult-onset PTD. In family members aged 20 to 45 years vs controls (mean + 2.5 SD), abnormal SDTs were found in four of five affected with adult-onset PTD and in 12 of 49 unaffected relatives. Sensory...
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