Article
Clinical, genetic, and pathologic characteristics of patients with frontotemporal dementia and progranulin mutations.
Archives of neurology - 1 Aug 2007
Van Deerlin Vivianna M, Wood Elisabeth McCarty, Moore Peachie, Yuan Wuxing, Forman Mark S, Clark Christopher M, Neumann Manuela, Kwong Linda K, Trojanowski John Q, Lee Virginia M-Y, Grossman Murray
Abstract excerpt
BACKGROUND: Patients with frontotemporal dementia due to mutation of progranulin may have a distinct phenotype. OBJECTIVE: To identify distinct clinical and pathologic features of patients with frontotemporal dementia who have mutations of progranulin (GRN). DESIGN: Retrospective clinical-pathologic study. SETTING: Academic medical center. PATIENTS: Twenty-eight patients with frontotemporal dementia, including 9...
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