Article
Role for the Wilms tumor gene in genital development?
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990
van Heyningen V, Bickmore W A, Seawright A, Fletcher J M, Maule J, Fekete G, Gessler M, Bruns G A, Huerre-Jeanpierre C, Junien C
Abstract excerpt
Detailed molecular definition of the WAGR region at chromosome 11p13 has been achieved by chromosome breakpoint analysis and long-range restriction mapping. Here we describe the molecular detection of a cytogenetically invisible 1-megabase deletion in an individual with aniridia, cryptorchidism,...
Topics
- Aniridia
- Child
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Cryptorchidism
- DNA Probes
- Humans
- Hypospadias
- Kidney Neoplasms
- Male
- Mutation
- Restriction Mapping
- Wilms Tumor