Article
Genetic susceptibility to retinopathy of prematurity: the evidence from clinical and experimental animal studies.
The British journal of ophthalmology - 1 Dec 2007
Holmström Gerd, van Wijngaarden Peter, Coster Douglas J, Williams Keryn A
Abstract excerpt
Despite advances in management and treatment, retinopathy of prematurity remains a major cause of childhood blindness. Evidence for a genetic basis for susceptibility to retinopathy of prematurity is examined, including the influences of sex, ethnicity, and ocular pigmentation. The role of polymorphisms is explored in the genes for vascular endothelial growth factor and insulin-like growth factor-1, and of...
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