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Article

Comprehensive gene-expression profile in murine oxygen-induced retinopathy

6 Oct 2008

Abstract excerpt

BACKGROUND/AIMS: To investigate the correlation between the clinical course and gene-expression pattern in murine oxygen-induced retinopathy (OIR), a commonly used model of retinopathy of prematurity (ROP). METHODS: OIR was induced in C57BL/6N mice by placing postnatal day 7 (P7) pups in 75% oxygen for 5 days. The clinical course of the OIR was evaluated on retinal flat-mounts after fluorescein...

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PMID: 18838407
DOI: 10.1136/bjo.2008.142646

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