Article
Evaluation of global clustering patterns and strain variation over an extended ORF26 gene locus from Kaposi's sarcoma herpesvirus.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Sept 2007
Zong Jian-Chao, Kajumbula Henry, Boto William, Hayward Gary S
Abstract excerpt
BACKGROUND: Small 233-bp or 330-bp DNA fragments of the ORF26 gene of human Kaposi's sarcoma herpesvirus (KSHV) have been used extensively to identify KSHV by PCR in clinical samples; to associate KSHV with novel diseases and to correlate KSHV strain differences with pathogenicity. OBJECTIVES: We evaluated the nature, extent and source of nucleotide sequence variability among a large and diverse set of known...
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