Article
Reflections on the interpretation of heterogeneity and strain differences based on very limited PCR sequence data from Kaposi's sarcoma-associated herpesvirus genomes.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Sept 2007
Zong Jian-Chao, Arav-Boger Ravit, Alcendor Donald J, Hayward Gary S
Abstract excerpt
Ever since the original identification of fragments of KSHV DNA in Kaposi's sarcoma (KS) tissue by Chang et al. in 1994, PCR has been used successfully and extensively to detect the virus in clinical samples from the accepted etiological diseases of KS, PEL and MCD. However, a number of other clinical and epidemiological studies claiming evidence for KSHV in multiple myeloma or sarcoid and more recently in...
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