Article
Genotypic analysis at multiple loci across Kaposi's sarcoma herpesvirus (KSHV) DNA molecules: clustering patterns, novel variants and chimerism.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2002
Zong Jianchao, Ciufo Dolores M, Viscidi Raphael, Alagiozoglou Lee, Tyring Stephen, Rady Peter, Orenstein Jan, Boto William, Kalumbuja Henry, Romano Nino, Melbye Mads, Kang Gyeong H, Boshoff Chris, Hayward Gary S
Abstract excerpt
BACKGROUND: The genomes of human Kaposi's sarcoma-associated herpesvirus (KSHV) display several levels of DNA sequence heterogeneity and subgrouping that show distinctive clustering patterns in related human populations. The four major subtype patterns for the hypervariable ORF-K1 protein correlate closely with the principal diasporas resulting from the migration of modern humans out of East Africa and suggest...
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