Article
Molecular analysis of human herpesvirus 8 by using single nucleotide polymorphisms in open reading frame 26.
Journal of clinical microbiology - 1 Jun 2003
Endo Tokiomi, Miura Toshiyuki, Koibuchi Tomohiko, Nakamura Hitomi, Takahashi Takashi, Odawara Takashi, Goto Mieko, Ajisawa Atsushi, Iwamoto Aikichi, Nakamura Tetsuya
Abstract excerpt
Human herpesvirus 8 (HHV-8) can be classified into distinct subtypes on the basis of sequence polymorphisms in several open reading frames (ORFs). We analyzed the subtypes of HHV-8 in 59 human immunodeficiency virus-infected Japanese patients by using polymorphisms in ORF26 and found that over two-thirds of the HHV-8 isolates fell into major subtype A. We also found that single nucleotide polymorphisms (SNPs) at...
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