Article
Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction.
American journal of physiology. Renal physiology - 1 Oct 2007
Chen G, Bridenbaugh E A, Akintola A D, Catania J M, Vaidya V S, Bonventre J V, Dearman A C, Sampson H W, Zawieja D C, Burghardt R C, Parrish A R
Abstract excerpt
Aging is associated with an increased incidence and severity of acute renal failure. However, the molecular mechanism underlying the increased susceptibility to injury remains undefined. These experiments were designed to investigate the influence of age on the response of the kidney to ischemic...
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