Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-335 and miR-34a Promote renal senescence by suppressing mitochondrial antioxidative enzymes.

Journal of the American Society of Nephrology : JASN - 1 Jul 2011

Bai Xue-Yuan, Ma Yuxiang, Ding Rui, Fu Bo, Shi Suozhu, Chen Xiang-Mei

Abstract excerpt

The molecular basis for aging of the kidney is not well understood. MicroRNAs (miRNAs) contribute to processes such as development, differentiation, and apoptosis, but their contribution to the aging process is unknown. Here, we analyzed the miRNA expression profile of young (3-month) and old (24-month) rat kidneys and identified the biologic pathways and genes regulated by differentially expressed miRNAs. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Down-Regulation
Share to Kidney

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNAs

Share to Mitochondria

Share to Oxidative Stress

Share to Rats, Wistar

Share to Superoxide Dismutase

Source

Open in PubMed Open full text

Identifiers

PMID: 21719785
DOI: 10.1681/ASN.2010040367
PMCID: PMC3137573

Genes

SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-335 and miR-34a Promote renal senescence by suppressing mitochondrial antioxidative enzymes.PMID 21719785Read ↗

Kidney Aging and Chronic Kidney DiseaseSemantic proximity Read ↗

Cellular senescence and kidney agingSemantic proximity Read ↗

Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged KidneysSemantic proximity Read ↗

Epigenetically regulated inflammation in vascular senescence and renal progression of chronic kidney diseaseSemantic proximity Read ↗

Mechanisms of Cardiovascular Disorders in Patients With Chronic Kidney Disease: A Process Related to Accelerated SenescenceSemantic proximity Read ↗

Inflammation and Premature Ageing in Chronic Kidney Disease.Semantic proximity Read ↗

Upregulated PD-1 signaling antagonizes glomerular health in aged kidneys and diseaseSemantic proximity Read ↗

A Transcriptional Profile of Aging in the Human KidneySemantic proximity Read ↗

Predict the role of lncRNA in kidney aging based on RNA sequencingSemantic proximity Read ↗

Sirt3 Attenuates Oxidative Stress Damage and Rescues Cellular Senescence in Rat Bone Marrow Mesenchymal Stem Cells by Targeting Superoxide Dismutase 2Semantic proximity Read ↗

Age and sex differences in kidney microRNA expression during the life span of F344 ratsSemantic proximity Read ↗

Podocyte Senescence and AgingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.