Article
Comparative evaluation of stable TAFIa variants: importance of alpha-helix 9 and beta-sheet 11 for TAFIa (in)stability.
Journal of thrombosis and haemostasis : JTH - 1 Oct 2007
Ceresa E, De Maeyer M, Jonckheer A, Peeters M, Engelborghs Y, Declerck P J, Gils A
Abstract excerpt
BACKGROUND: Activated thrombin activatable fibrinolysis inhibitor (TAFIa) plays a pivotal role in fibrinolysis. TAFIa activity is regulated by a temperature-dependent instability. This instability has not only complicated the study of structure-function relationships of TAFIa but has also prevent...
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