Article
Inappropriate intracranial hemodynamics in the natural course of MELAS.
Brain & development - 1 Feb 2008
Nishioka Junko, Akita Yukihiro, Yatsuga Shuichi, Katayama Koujyu, Matsuishi Toyojiro, Ishibashi Masatoshi, Koga Yasutoshi
Abstract excerpt
The abnormalities of intracranial hemodynamics associated with strokelike episodes in MELAS are variable depend on the time phase from the onset of strokelike episodes and on the progression of the dementia state. To clarify the regional cerebral blood flows (rCBF) in the natural course of MELAS is very important to understand the pathogenic mechanism of this disorder, either cytopathy, angiopathy or both. We...
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