Article
Additional sex combs affects antennal development by means of spatially restricted repression of Antp and wg.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2007
Halachmi Naomi, Schulze Karen L, Inbal Adi, Salzberg Adi
Abstract excerpt
Additional sex combs (Asx) is thought to function in protein complexes of both the Trithorax and Polycomb groups, but very little is known about its developmental roles. Here, we present a detailed analysis of Asx's role in antennal development. We show that loss of Asx in the antennal disc causes a complex phenotype, which consists of distal antenna-to-leg transformations and outgrowth of ectopic leg-like...
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