Article
Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters.
American journal of physiology. Cell physiology - 1 Aug 2007
Morgan Patricio E, Pastoreková Silvia, Stuart-Tilley Alan K, Alper Seth L, Casey Joseph R
Abstract excerpt
Association of some plasma membrane bicarbonate transporters with carbonic anhydrase enzymes forms a bicarbonate transport metabolon to facilitate metabolic CO(2)-HCO(3)(-) conversions and coupled HCO(3)(-) transport. The transmembrane carbonic anhydrase, CAIX, with its extracellular catalytic site, is highly expressed in parietal and other cells of gastric mucosa, suggesting a role in acid secretion. We examined...
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