Article
Muscle lymphocytic infiltrates in thymoma-associated myasthenia gravis are phenotypically different from those in polymyositis.
Neuromuscular disorders : NMD - 1 Dec 2007
Zamecnik Josef, Vesely Dan, Jakubicka Branislav, Simkova Libuse, Pitha Jiri, Schutzner Jan, Mazanec Radim, Vogel Hannes
Abstract excerpt
The aim of the study is to provide evidence that the lymphocytic infiltration of myasthenia gravis (MG) muscle do not represent a true autoimmune myositis, rather an infiltration by naive lymphocytes derived from lymphocyte-rich thymomas. Muscle biopsies from 179 patients with pure MG, 6 thymoma patients without MG and 15 patients with definite polymyositis were analyzed. In 18 patients with MG (all associated...
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