Article
Gene prioritization through genomic data fusion.
Nature biotechnology - 1 May 2006
Aerts Stein, Lambrechts Diether, Maity Sunit, Van Loo Peter, Coessens Bert, De Smet Frederik, Tranchevent Leon-Charles, De Moor Bart, Marynen Peter, Hassan Bassem, Carmeliet Peter, Moreau Yves
Abstract excerpt
The identification of genes involved in health and disease remains a challenge. We describe a bioinformatics approach, together with a freely accessible, interactive and flexible software termed Endeavour, to prioritize candidate genes underlying biological processes or diseases, based on their similarity to known genes involved in these phenomena. Unlike previous approaches, ours generates distinct...
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