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Article

Therapeutic strategy using phenotypic modulation of cancer cells by differentiation-inducing agents.

Cancer science - 1 Nov 2007

Honma Yoshio, Akimoto Miho

Abstract excerpt

A low concentration of differentiation inducers greatly enhances the in vitro and in vivo antiproliferative effects of interferon (IFN)alpha in several human cancer cells. Among the differentiation inducers tested, the sensitivity of cancer cells to IFNalpha was most strongly affected by cotylenin A. Cotylenin A, which is a novel fusicoccane diterpene glycoside with a complex sugar moiety, affected the...

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Identifiers

PMID: 17645578
DOI: 10.1111/j.1349-7006.2007.00575.x
PMCID: PMC11158768

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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