Article
The second messenger bis-(3'-5')-cyclic-GMP and its PilZ domain-containing receptor Alg44 are required for alginate biosynthesis in Pseudomonas aeruginosa.
Molecular microbiology - 1 Aug 2007
Merighi Massimo, Lee Vincent T, Hyodo Mamoru, Hayakawa Yoshihiro, Lory Stephen
Abstract excerpt
The ubiquitous bacterial second messenger c-di-GMP regulates the expression of various virulence determinants in a wide range of bacterial pathogens. Several studies have suggested that proteins with a PilZ domain function as c-di-GMP receptors. We have identified in the Pseudomonas aeruginosa ge...
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