Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MRI findings and genotype analysis in patients with childhood onset growth hormone deficiency--correlation with severity of hypopituitarism.

Journal of pediatric endocrinology & metabolism : JPEM - 1 May 2007

Zimmermann Anca, Schenk Jens-Peter, Grigorescu Sido Paula, Pfaffle Roland, Lazea Cecilia, Zimmermann Tim, Heinrich Udo, Weber Matthias M, Bettendorf Markus

Abstract excerpt

AIM: To evaluate the relationship between pituitary size, PIT1 and PROP1 genotype, and the severity of childhood onset growth hormone deficiency (coGHD). PATIENTS: Forty-four patients with coGHD (34 M; 9.7 +/- 4.1 years): severe isolated (SI) GHD (n = 14); partial isolated (PI) GHD (n=13); multiple pituitary hormone deficiencies (MPHD) (n=17). RESULTS: Pituitary abnormalities were found in 7/14 patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Body Height

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dwarfism, Pituitary

Share to Homeodomain Proteins

Share to Hypopituitarism

Share to Magnetic Resonance Imaging

Share to Pituitary Gland

Share to Transcription Factor Pit-1

Source

Identifiers

PMID: 17642419
DOI: 10.1515/jpem.2007.20.5.587

Genes

SDS
PROP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MRI findings and genotype analysis in patients with childhood onset growth hormone deficiency--correlation with severity of hypopituitarism.PMID 17642419Read ↗

Phenotype and radiological correlation in patients with growth hormone deficiency.Semantic proximity Read ↗

Associations between pituitary imaging abnormalities and clinical and biochemical phenotypes in children with congenital growth hormone deficiency: data from an international observational study.Semantic proximity Read ↗

Classical and non-classical causes of GH deficiency in the paediatric age.Semantic proximity Read ↗

Identification of novel GHRHR and GH1 mutations in patients with isolated growth hormone deficiency.Semantic proximity Read ↗

Comparison of clinical characteristics of a pediatric cohort with combined pituitary hormone deficiency caused by mutation of the PROP1 gene or of other origins.Semantic proximity Read ↗

Pituitary magnetic resonance imaging and function in patients with growth hormone deficiency with and without mutations in GHRH-R, GH-1, or PROP-1 genes.Semantic proximity Read ↗

Clinical characteristics of a pediatric cohort of patients with combined pituitary insufficiency caused by mutations of the PROP1 geneSemantic proximity Read ↗

MR imaging of the pituitary gland in children and young adults with congenital combined pituitary hormone deficiency associated with PROP1 mutations.Semantic proximity Read ↗

Magnetic resonance imaging of the hypothalamus-pituitary unit in childrensuspected of hypopituitarism: who, how and when toinvestigate.Semantic proximity Read ↗

Isolated GH deficiency (IGHD) type II: imaging of the pituitary gland by magnetic resonance reveals characteristic differences in comparison with severe IGHD of unknown origin.Semantic proximity Read ↗

Familial combined pituitary hormone deficiency caused by PROP-1 gene mutation. Growth patterns and MRI studies in untreated subjects.Semantic proximity Read ↗

Mutations and pituitary morphology in a series of 82 patients with PROP1 gene defects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.