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Article

Mutations and pituitary morphology in a series of 82 patients with PROP1 gene defects.

Hormone research in paediatrics - 1 Jan 2011

Obermannova Barbora, Pfaeffle Roland, Zygmunt-Gorska Agata, Starzyk Jerzy, Verkauskiene Rasa, Smetanina Natalija, Bezlepkina Olga, Peterkova Valentina, Frisch Herwig, Cinek Ondrej, Child Christopher J, Blum Werner F, Lebl Jan

Abstract excerpt

BACKGROUND/AIMS: Defects of the PROP1 gene are the most prevalent genetic cause of combined pituitary hormone deficiency. Previous observations in affected patients have shown pituitary size ranging from hypoplasia to overt pituitary mass and evolution of size over the lifespan. METHODS: We evaluated pituitary size and morphology in PROP1-mutation carriers who originated from Central and Eastern Europe. We...

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Identifiers

PMID: 22024773
DOI: 10.1159/000332693

Genes

PROP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations and pituitary morphology in a series of 82 patients with PROP1 gene defects.PMID 22024773Read ↗

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