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Article

Classical and non-classical causes of GH deficiency in the paediatric age.

Best practice & research. Clinical endocrinology & metabolism - 1 Dec 2016

Di Iorgi Natascia, Morana Giovanni, Allegri Anna Elsa Maria, Napoli Flavia, Gastaldi Roberto, Calcagno Annalisa, Patti Giuseppa, Loche Sandro, Maghnie Mohamad

Abstract excerpt

Growth hormone deficiency (GHD) may result from a failure of hypothalamic GHRH production or release, from congenital disorders of pituitary development, or from central nervous system insults including tumors, surgery, trauma, radiation or infiltration from inflammatory diseases. Idiopathic, isolated GHD is the most common sporadic form of hypopituitarism. GHD may also occur in combination with other pituitary...

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Source

Identifiers

PMID: 27974186
DOI: 10.1016/j.beem.2016.11.008

Genes

ARNT2
CDON
CHD7
FGF8
FGFR1
GHRH
GLI2
GLI3
HESX1
IGSF1
LHX3
LHX4
NFKB2
OTX2
PAX6
PROK2
PROKR2
PROP1
SOX2
SOX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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