Article
Cytogenetic aberrations and immunoglobulin VH gene mutations in clinically benign CD5- monoclonal B-cell lymphocytosis.
American journal of clinical pathology - 1 Aug 2007
Amato Dominick, Oscier David G, Davis Zadie, Mould Sarah, Zheng Jianing, Kolomietz Elena, Wang Chen
Abstract excerpt
The finding of monoclonal B-cell lymphocytosis (MBL) raises questions on the nature of clonal cell expansion and its risk of progression. We identified and characterized 7 cases of clinically benign clonal B-cell lymphocytosis. The clonal lymphocytes were clearly of CD5- and non-chronic lymphocytic leukemia (CLL) phenotype. All cases had mild to moderate absolute lymphocytosis. The clonal population accounted for...
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