Article
H63D mutation of the hemochromatosis gene and serum ferritin levels in Thai thalassemia carriers.
Acta haematologica - 1 Jan 2007
Yamsri Supawadee, Sanchaisuriya Kanokwan, Fucharoen Supan, Fucharoen Goonnapa, Jetsrisuparb Arunee, Wiangnon Surapon, Changtrakul Yossombat, Sanchaisuriya Pattara
Abstract excerpt
We determined the prevalence of the H63D and the IVS5#1G-A HFE mutations in 370 (169 males and 201 females) Thai thalassemia carriers and 201 normal subjects. While no IVS5#1G-A mutation was found, the H63D heterozygosity was identified in 5.5% (11/201) of normal subjects and 7.3% (27/370) of thalassemia carriers. Within the thalassemic group, the medians (ranges) of serum ferritin were 217.5 ng/ml (20.1-424.3)...
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