Article
Association of HFE Gene Mutations With Serum Ferritin Level and Heart and Liver Iron Overload in Patients With Transfusion-dependent Beta-Thalassemia.
Journal of pediatric hematology/oncology - 1 Jan 2021
Zekavat Omid Reza, Zareian Jahromi Mahshid, Haghpanah Sezaneh, Kargar Jahromi Zahra, Cohan Nader
Abstract excerpt
OBJECTIVE: This study was performed on patients with transfusion-dependent beta-thalassemia (TDT) to investigate the effect of HFE gene mutations of iron overload in a large group of patients with TDT major and its relationship with heart and liver T2* magnetic resonance imaging (MRI) level. MATERIALS AND METHODS: In a cross-sectional study, a total of 253 patients with TDT who had regular blood transfusion were...
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