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Article

Investigation of correlation between H63D and C282Y mutations in HFE gene and serum Ferritin level in beta-thalassemia major patients.

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine - 1 Nov 2019

Rahmani Romina, Naseri Parisa, Safaroghli-Azar Ava, Tarighi Shahriar, Hosseini Tahereh, Hojjati Mohammad Taher

Abstract excerpt

INTRODUCTION: Mutations in the HFE gene have been shown to be associated with hemochromatosis which is observed in beta-thalassemia major. In this study, we determined the HFE gene mutations (C282Y and H63D) among b-thalassemia major patients to investigate the effect of these mutations on serum Ferritin levels. MATERIAL AND METHODS: In this cross-sectional study, a total of 105 b-thalassemia subjects with a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31679808
DOI: 10.1016/j.tracli.2019.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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