Article
A review of histopathological subtypes of ovarian cancer in BRCA-related French Canadian cancer families.
Familial cancer - 1 Jan 2007
Tonin Patricia N, Maugard Christine M, Perret Chantal, Mes-Masson Anne-Marie, Provencher Diane M
Abstract excerpt
Pathogenic mutations in BRCA1 and BRCA2 have been reported in about 55-59% of breast and ovarian cancer (HBOC) families of French Canadian descent, where about 70% of families with more than two cases of ovarian cancer were mutation-positive. Given that specific subtypes of ovarian cancer are associated with mutation-positive families, we reviewed the features of 54 HBOC families of French Canadian descent that...
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