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Article

A targeted analysis identifies a high frequency of BRCA1 and BRCA2 mutation carriers in women with ovarian cancer from a founder population.

Journal of ovarian research - 27 Mar 2015

Belanger Moria H, Dolman Lena, Arcand Suzanna L, Shen Zhen, Chong George, Mes-Masson Anne-Marie, Provencher Diane, Tonin Patricia N

Abstract excerpt

BACKGROUND: The frequency of BRCA1 and BRCA2 mutations in ovarian cancer patients varies depending on histological subtype and population investigated. The six most commonly recurring BRCA1 and BRCA2 mutations previously identified in a founder French Canadian population were investigated in 439 histologically defined ovarian, fallopian tube and primary peritoneal cancer cases that were ascertained at one...

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Source

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Identifiers

PMID: 25884701
DOI: 10.1186/s13048-015-0124-8
PMCID: PMC4376165

Genes

BRCA1
BRCA2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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