Article
Aggregating phenotype in Lactobacillus crispatus determines intestinal colonization and TLR2 and TLR4 modulation in murine colonic mucosa.
Clinical and vaccine immunology : CVI - 1 Sept 2007
Voltan Sandra, Castagliuolo Ignazio, Elli Marina, Longo Stefano, Brun Paola, D'Incà Renata, Porzionato Andrea, Macchi Veronica, Palù Giorgio, Sturniolo Giacomo C, Morelli Lorenzo, Martines Diego
Abstract excerpt
The colonic microbiota is a major modulator of the mucosal immune system; therefore, its manipulation through supplementation with probiotics may significantly affect the host's immune responses. Since different probiotics seem to exert various effects in vivo, we tested the relevance of the autoaggregation phenotype on the intestinal persistence of lactobacilli and their ability to modulate the host's innate...
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